Few things to try:
1. Turn down audio acceleration [control panel | sounds and audio devices (item) | audio (tab) | advanced (button) | performance (tab)]
2. Turn down video acceleration [somehow]
3. Hit the machine with a large mallet
4. Uninstall the audio drivers BUT KEEP THE CARD IN and try again (identify if its possibly an audio driver problem)
5. Borrow a GF4 off a mate and see if the problem is still there
6. Hit the machine with a large mallet. Again.
7. Try your soundcard and video card in someone elses machine (same OS though!)
8. Tinker more with the BIOS
That's all I can think of right now.